GPCR – APBN New Site

Finding the “Switchman” Responsible for Biased Signalling

March 12, 2022 . Posted in Eye on China, Vol 26 No 3 & 4

By uncovering the amino acid essential for recognising GPCR ligands, biased signalling of CCL15 can be restricted, presenting an attractive drug target for treating asthma. Asthma is one of the most...

Targeting Cell Signalling Components for Disease Treatment

April 25, 2021 . Posted in Bioboard

Researchers from Duke-NUS Medical School in Singapore and Columbia University in the US have solved how Wnt proteins, which play a fundamental role in cell proliferation and differentiation, hitch a...