Using a combinatorial CRISPR-Cas9 screening platform, researchers have demonstrated how this novel two-drug regime can be used in combination with sorafenib to curb tumour cell growth. Accounting for...
As humankind progresses into a new era of science and technology, many natural hazards have been eliminated and selection pressures lessened. While the natural evolution of the human species...
Using Drosophila, a group of scientists from Zhejiang University demonstrated how abnormal mitochondrial tRNA metabolism can lead to developmental delay and seizure. Mitochondrial aminoacyl-tRNA...
A new, compact CRISPR-Cas system can now precisely and efficiently shuttle gene-editing tools into mammalian cells, overcoming present challenges in genome engineering. Most gadgets today are...
A new type I-F CRISPR-Cas system has been developed to be transferrable to heterologous hosts and demonstrates promising efficiency, stability, and “scarless” gene-editing, opening up a new...
Researchers from the University of California San Diego have constructed a new genetic toolkit using CRISPR technology to innovate gene drives for Culex mosquitoes and other pathogen-carrying...
Using CRISPR technology, researchers at the University of Tsukuba creates albino sea urchins for hope that it would be brought back to the forefront of studies in developmental biology. In...
Systematic deletion of every gene in the genome reveals 'druggable' pathways that help keep muscle cells healthy. A new study led by Louis Kunkel, PhD, and research fellow Angela Lek, PhD at Boston...
Researchers from Osaka University broaden understanding of Class 1 CRISPR gene editing system in human cells. CRISPR – short for “clusters of regularly interspaced short palindromic repeats”...
Safer techniques of DNA base editing produces potential for therapeutic potential. A new and safer solution has been worked out by researchers to tackle with the problem of off-target RNA mutations...
Updated regulations allow scientists to use some genome-editing techniques in plants and animals without government approval. The Australian government will not regulate the use of gene-editing...
Research found popular gene-editing tool likely to cause off-target mutations. Chinese scientists found that a popular gene-editing tool may lead to wide off-target mutations, warning of serious...