These new organoids suggest that the extracellular matrix of tumours may be more important in regulating therapeutic response and efficacy of anti-cancer drugs than initially thought. With an...
This new bottom-up design strategy could be integrated into the creation of molecular machines and robots, potentially advancing nanopore technology. Biological nanopores are generally created by...
For the first time, scientists successfully transplanted stem cell-based microrobots efficiently, non-invasively, and safely into mice brain tissues to treat neurological diseases. A joint research...
This mRNA vaccine successfully prevented the development of Lyme disease in guinea pigs after tick bite and removal. Caused by the bacterium B. burgdorferi and more rarely, B. mayonii, Lyme...
A single amino acid change in a tumour suppressor protein extends health while maintaining longevity in roundworms. According to the World Health Organization, 1 in every 6 people or around 1.4...
Feeding obese mice with the natural bioavailable BDNF mimetic, 7,8-dihydroxyflavone, successfully alleviated obesity-induced mitochondrial dysfunction. Obesity is a major risk factor for various...
As a proof of principle, scientists showed that encapsulating whole-cell vaccines using metal-organic frameworks can induce long-term and durable immune responses and significantly improve survival...
Candesartan, which suppresses the accumulation of extracellular matrix proteins in the vessel wall of a mouse model, shows promise for treating age-related cerebral arteriopathy. Cerebral small...
A deficiency of this protein slows down wound healing in cutaneous ischemia-reperfusion injuries by promoting inflammation and apoptosis. Ischemia is a condition in which blood flow, and consequently...
Artificially designed cone snail insulin analogues reportedly bind better and more strongly to the human insulin receptor than the naturally occurring human insulin hormone. Plaguing around 463...
The National Centre for the 3Rs would promote the adoption of the 3R principles of Replace, Reduce, Refine. Taiwan’s Vice President William Lai loudly declared his support for the development of...
Start-up Revivo BioSystems has developed technology that uses a model of human skin for testing, which is cost-efficient, ethical, and reliable. Dr. Massimo Alberti, CEO and Founder of Revivo...