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Artificial Intelligence tool in Mammography to Boost Breast Cancer Detection

Researchers develop artificial intelligence algorithms to facilitate cancer detection in breast tissue that is applicable with mammography.

The use of artificial intelligence (AI) has been largely studied for its positive applications in the medical field. It can enhance the performance of radiologists in reading breast cancer screening mammograms, according to a study published in Radiology: Artificial Intelligence.

Breast cancer screening with mammography has been shown to improve prognosis and reduce mortality by detecting disease at an earlier, more treatable stage. However, many cancers are missed on screening mammography, and suspicious findings often turn out to be benign. An earlier study from Radiology found that, on average, only 10 percent of women are recalled from screening for additional diagnostic tests due suspicious findings are ultimately found to have cancer.

AI-based algorithms represent a promising avenue for improving the accuracy of digital mammography. Developers “train” the AI system using existing images, allowing the software it to recognize abnormalities associated with cancer and distinguish them from benign findings. This technology provides the potential for better cancer detection and improved efficiency for radiologists.

In this recent study, researchers used MammoScreen, an AI tool that can be applied with mammography to aid in cancer detection. The AI system is designed to identify regions suspicious for breast cancer on 2D digital mammograms and assess their likelihood of malignancy. The system takes as input the complete set of four views composing a mammogram and outputs a set of image positions with a related suspicion score.

Fourteen radiologists assessed a dataset of 240 images acquired between 2013 and 2016 that included different types of abnormalities. Half of the dataset was read without AI and the other half with the help of AI during a first session and without during a second session.

Average sensitivity for cancer increased slightly when using AI support. AI also helped reduce the rate of false negatives, or findings that look normal even though cancer is present.

“The results show that MammoScreen may help to improve radiologists’ performance in breast cancer detection,” said Serena Pacilè, Ph.D., clinical research manager at Therapixel, where the software was developed.

The improved diagnostic performance of radiologists in the detection of breast cancer was achieved without prolonging their workflow. In cases with a low likelihood of malignancy, reading time decreased in the second reading session. The researchers shared that reduced reading time could increase overall efficiency, allowing radiologists to focus their attention on the more suspicious examinations.

In March, the U.S. Food and Drug Administration cleared MammoScreen for use in the clinic, where it could help reduce the workload of radiologists, according to Dr. Pacilè.

The researchers plan to explore the behaviour of the AI tool on a large screening-based population and its ability to detect breast cancer earlier. [APBN]